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HBV Epidemiology & Mortality

ICAAC 2012: Hepatitis B Vaccine Effective Long-term, but Some Lose Protection after 15 Years

Nearly all children who received 3 doses of the Engerix-B hepatitis B vaccine achieved protective immunity, but about 20% fell below the protective antibody threshold by year 15 and could benefit from a booster shot, Canadian researchers reported at the 52nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2012) this week in San Francisco. alt

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Hepatitis B Rates Higher than Expected among Gay Men, Drug Users, Vaccinated Babies

altAn unexpectedly high proportion of gay/bisexual men and injection drug users develop chronic hepatitis B rather than clearing the infection, Amsterdam researchers reported in the September 2012 Journal of Hepatology. Other recent studies found that more than one-quarter of children born to mothers with hepatitis B showed evidence of "occult" HBV infection despite vaccination at birth, and that some individuals vaccinated as children may still show evidence of infection as adults.

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Hepatitis C Deaths Now Outnumber Deaths from HIV; Screening Cost-Effective for Baby Boomers

More people are now dying due to hepatitis C than due to HIV in the U.S., according to CDC researchers, a shift attributable to both the aging of "baby boomers" infected with hepatitis C virus (HCV) many years ago and the large reduction in HIV/AIDS-related mortality; hepatitis B deaths, however, are far lower than either hepatitis C or HIV. Another recent study showed that HCV screening for everyone in the 45-65 age range is likely to be cost-effective.alt

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More than 2 Million People in U.S. May Have Chronic Hepatitis B

The prevalence of chronic hepatitis B virus (HBV) infection in the U.S. may be as high as 2.2 million -- greater than previously estimated -- with the highest numbers of cases occurring among foreign-born individuals, especially those from Asia and Africa.alt

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AASLD 2011: Natural History of Hepatitis B Infection and Role of HBV Genotype

People with hepatitis B "e" antigen (HBeAg) positive and negative disease have different levels of hepatitis B surface antigen (HBsAg), variable extent of liver fibrosis, and different distribution of HBV genotypes, according to a study presented at the American Association for the Study of Liver Disease (AASLD) Liver Meeting last month in San Francisco.alt

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