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U.S. Hepatitis B Prevalence in the U.S. in the HBV Vaccine Era

The prevalence of past and present hepatitis B virus (HBV) infection fell by nearly 70% among children in a large household survey of U.S. residents a decade after the introduction of universal HBV vaccination, according to a report by Centers for Disease Control and Prevention (CDC) researchers published in the July 15, 2010 Journal of Infectious Diseases. Hepatitis B prevalence among adults remains high, however, varying considerably among racial/ethnic groups and much greater among foreign-born individuals.

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Safety Review Clears Continuation of Hepislav Hepatitis B Vaccine

Dynavax Technologies announced this week that a Data Safety Monitoring Board has reviewed interim data from more than 2000 participants in 2 Phase 3 studies of the company's investigational hepatitis B vaccine, Hepislav, and determined that the trial may go forward without modification.

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Investigational 2-Dose Dynavax Heplisav Hepatitis B Vaccine May Work Better than Standard 3-Dose Energix-B Vaccine

An investigational hepatitis B virus (HBV) vaccine may offer the same degree of protection with 2 doses as the standard Engerix-B vaccine does with 3 doses, according to a study presented at the 44th Annual Meeting of the European Association for the Study of the Liver (EASL 2009) last month in Copenhagen.

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