HIV/AIDS Topics Delaying Treatment More than 12 Months after HIV Infection Reduces CD4 Cell Recovery
- Details
- Category: HIV Treatment
- Published on Tuesday, 25 November 2014 00:00
- Written by Liz Highleyman
People with HIV who start antiretroviral therapy (ART) more than a year after seroconversion have a lower likelihood of regaining normal CD4 T-cell counts, researchers reported in the November 24 online edition of JAMA Internal Medicine. "If full restoration of immunologic and clinical health is our goal, then the present study tells us that the best chance we have is to start antiretroviral therapy within 12 months of infection," according to an accompanying editorial.
HIV Superinfection May Boost Viral Load but Does Not Worsen Disease Progression
- Details
- Category: HIV Disease Progression
- Published on Friday, 03 October 2014 00:00
- Written by Liz Highleyman
Superinfection with a second strain of HIV may lead to a more rapid increase in plasma HIV RNA levels, but apparently does not contribute much to CD4 T-cell loss or disease progression, according to a study published in the September 24 edition of AIDS.
Inherited Low Cholesterol in Immune Cells Linked to Slower HIV Disease Progression
- Details
- Category: HIV Disease Progression
- Published on Friday, 02 May 2014 00:00
- Written by UPMC/University of Pittsburgh
A genetic variation linked to lower levels of intracellular cholesterol is associated with reduced transmission of HIV between immune cells, which may contribute to slower evolution of disease in non-progressors, according to a report in the April 29, 2014, edition of the electronic journal mBio, published by the American Society for Microbiology.
Coverage of the 2014 International AIDS Conference
- Details
- Category: HIV Treatment
- Published on Thursday, 24 July 2014 00:00
- Written by HIVandHepatitis.com
HIVandHepatitis.com coverage of the 20th International AIDS Conference (AIDS 2014), July 20-25, in Melbourne, Australia.
Conference highlights include biomedical HIV prevention (PrEP and treatment-as-prevention), HIV cure research, interferon-free therapy for hepatitis C and HIV/HCV coinfection, access to treatment, and fighting stigma and criminalization of key affected populations.
7/25/14
CROI 2014: Cumulative Viral Load and HIV Disease Progression
- Details
- Category: HIV Disease Progression
- Published on Tuesday, 25 March 2014 00:00
- Written by Liz Highleyman
Periodic low-level viral load appears to predict virological failure, but not progression to AIDS or death, and cumulative viral load over time may be a risk factor for HIV disease progression and mortality, according to studies presented at the 21st Conference on Retroviruses and Opportunistic Infections (CROI 2014) this month in Boston.
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