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Immune Response to HIV

Immediate Antiretroviral Therapy Reduces HIV Infection of Resting CD4 T-Cells

Starting antiretroviral therapy (ART) during the acute phase of HIV infection appears to reduce the number of latently infected resting CD4 T-cells in most people, but this may not be the case for individuals with very few initially infected cells, according to a study published in the May 29, 2012, advance online edition of Proceedings of the National Academy of Sciences.alt

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More Gut Th17 Cells Linked to Better Control of HIV-like Virus in Monkeys

Rhesus macaque monkeys that had a larger number of a specific type of helper T-cells -- known as TH17 cells -- in their blood and intestinal tissue at the time of infection with SIV (a monkey virus related to HIV) had lower viral load set-points, according to a study published in the May 30, 2012, issue of Science Translational Medicine.alt

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Researchers Discover How HIV Neutralizing Antibodies Evolve

Researchers have shed further light on the development of broadly neutralizing antibodies against HIV, which are thought to be necessary for immune control and the virus and an effective vaccine, according to a study published in the August 11, 2011, advance online edition of Science.alt

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Cholesterol-depleted HIV Triggers Adaptive Immune Response

Removing cholesterol from HIV virus particles appears to inhibit their ability to damage CD4 T-cells, but causes them to stimulate an adaptive immune response, researchers reported in the September 9, 2011, advance online edition of the journal Blood. These findings offer clues that could aid the development of a protective HIV vaccine.alt

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Natural Killer Cells Play a Role in Immune Response against HIV

A type of immune system white blood cell known as natural killer or NK cells -- one of the first lines of defense against invading pathogens -- has been found to contribute to the body's immune response against HIV, according to a study reported in the August 3, 2011, issue of Nature alt

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