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Cardiovascular Disease

HIV Infection Associated with Increased Risk of Sudden Cardiac Death

People with HIV at a public clinic in San Francisco had a sudden cardiac death rate more than 4 times higher than that of the general population, and most who died had identifiable cardiovascular risk factors, according to a study described in the May 22, 2012, Journal of the American College of Cardiology.alt

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CROI 2012: Elevated Blood Pressure Linked to Heart Attack Risk in HIV+ People

HIV positive people with elevated blood pressure are at higher risk for myocardial infarction, or heart attack, even if they do not meet the definition for high blood pressure, researchers reported at the 19th Conference on Retroviruses and Opportunistic Infections (CROI 2012) this month in Seattle.alt

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Current HIV Protease Inhibitor Use Not Linked to Sudden Death or Stroke, but Cumulative Exposure Ups Risk

Current or recent use of HIV protease inhibitors was not associated with a significantly increased likelihood of sudden death or a first ischemic stroke among participants in the D:A:D cohort, according to a report in the February 2012 Journal of Infectious Diseases. Longer total cumulative use, however, did appear to raise the risk.alt

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CROI 2012: Metformin, Statins, and ACE Inhibitors May Reduce Cardiovascular Risk of People with HIV

The diabetes drug metformin can help stall progression of calcium build-up in the arteries of HIV positive people with metabolic abnormalities, potentially reducing their risk of cardiovascular events, researchers reported this month at the 19th Conference on Retroviruses and Opportunistic Infections (CROI 2012) in Seattle. Other studies found that statin drugs showed a trend toward lowering the risk of non-AIDS events and death, and an ACE inhibitor reduced blood pressure and certain inflammation biomarkers.

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IDSA 2011: Heart Problems Are Common Among People with HIV, but Largely Related to Modifiable Risk Factors

Structural and functional cardiac abnormalities were found in more than half of an HIV positive cohort in Washington, DC, according to a report at the 49th Annual Meeting of the Infectious Diseases Society of America (IDSA 2011) last month in Boston. Heart problems were often related to modifiable factors such as obesity and diabetes, suggesting that lifestyle changes may lower the risk.

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